Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8A1 All Species: 26.06
Human Site: T631 Identified Species: 47.78
UniProt: Q9Y2Q0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Q0 NP_006086.1 1164 131369 T631 A V Y Q R A S T S V Q N R L L
Chimpanzee Pan troglodytes XP_001150768 1164 131363 T631 A V Y Q R A S T S V Q N R L L
Rhesus Macaque Macaca mulatta XP_001099138 1164 131392 T631 A V Y Q R A S T S V Q N R L L
Dog Lupus familis XP_849357 1158 131123 Q628 Q R A S T S V Q N R L L K L E
Cat Felis silvestris
Mouse Mus musculus P70704 1149 129748 T616 A V Y H R A S T S V Q N R L L
Rat Rattus norvegicus XP_223390 1134 128100 R605 Q F A T E G L R T L C F A V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518853 932 104820 L408 V Q N R A L K L E E S Y E L I
Chicken Gallus gallus XP_420729 1223 137907 T690 D V Y H R A S T A I Q N R A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666697 916 102033 N392 T F I I L Y N N L I P I S L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137649 1324 149578 V792 Q T F D K A S V A L Q N R E S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200260 1167 132097 T618 A T Y Y K A S T A I Q N R E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XIE6 1213 137734 S654 E K F I Q A K S A L R D R E K
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 T781 S I Y N E A A T T L D N R A E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.8 96.9 N.A. 95.8 94.5 N.A. 74.4 88.5 N.A. 53.8 N.A. 50.9 N.A. N.A. 57.6
Protein Similarity: 100 100 100 98 N.A. 97.7 96.3 N.A. 76.9 92.4 N.A. 63.4 N.A. 65.4 N.A. N.A. 74.8
P-Site Identity: 100 100 100 6.6 N.A. 93.3 0 N.A. 6.6 66.6 N.A. 13.3 N.A. 33.3 N.A. N.A. 53.3
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 20 N.A. 20 80 N.A. 26.6 N.A. 60 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 39.2 39.9 N.A.
Protein Similarity: N.A. N.A. N.A. 58.6 57.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 16 0 8 70 8 0 31 0 0 0 8 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % D
% Glu: 8 0 0 0 16 0 0 0 8 8 0 0 8 24 24 % E
% Phe: 0 16 16 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 16 0 0 0 0 0 24 0 8 0 0 8 % I
% Lys: 0 8 0 0 16 0 16 0 0 0 0 0 8 0 8 % K
% Leu: 0 0 0 0 8 8 8 8 8 31 8 8 0 54 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 8 8 8 0 0 62 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 24 8 0 24 8 0 0 8 0 0 54 0 0 0 0 % Q
% Arg: 0 8 0 8 39 0 0 8 0 8 8 0 70 0 0 % R
% Ser: 8 0 0 8 0 8 54 8 31 0 8 0 8 0 8 % S
% Thr: 8 16 0 8 8 0 0 54 16 0 0 0 0 0 0 % T
% Val: 8 39 0 0 0 0 8 8 0 31 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 54 8 0 8 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _